Profiling Serum Bile Acid Glucuronides in Humans: Gender Divergences, Genetic Determinants, and Response to Fenofibrate
نویسندگان
چکیده
منابع مشابه
Profile of serum bile acids in non-cholestatic volunteers: gender-related differences in response to fenofibrate
Fenofibrate belongs to the group of hypolipidemic fibrates that act as activators of the peroxisome proliferator-activated receptor-α (PPARα), which is a regulator of bile acid synthesis, metabolism, and transport. The present study aimed at evaluating the effects of fenofibrate on the circulating bile acid profile in humans. A study population of 200 healthy individuals comprising both genders...
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Purpose: Toxoplasma gondii (T. gondii) is the causative agent of toxoplasmosis. It infects up to one third of the human population. The aim of this study was to evaluate the effects of T. gondii infection on induction of oxidative stress in serum of infected men and women. Materials and Methods: This case-control study was carried out on 150 individuals who had referred to our center ...
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Combined gas-liquid chromatography mass-spectroscopy was used to identify lithocholic acid and Confirm the presence of other bile acids in serum of a healthy fasting subject. GLC was used to measure deoxycholic (DCA), chenodeoxycholic (CDCA), and cholic (CA) acids in sera. Before analysis, serum bile acids were purified by (a) enzymatic hydrolysis of conjugates, (b) anion-exchange chromatograph...
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ژورنال
عنوان ژورنال: Clinical Pharmacology & Therapeutics
سال: 2013
ISSN: 0009-9236,1532-6535
DOI: 10.1038/clpt.2013.122